Fibromyalgia consists of widespread muscle pain and tenderness often accompanied by fatigue and altered sleep, memory, and mood. 

While symptoms are real, there is no evidence they are caused by disease or injury. 

If medical evaluations do not identify any disease or injury, or if treatments fail to provide expected improvement, it is likely that the brain plays a role in generating or contributing to the pain or illness. This is called a neuroplastic symptom.